Saturday, November 10, 2012

How Payers View Combo Therapy For Prostate Cancer // Pharmalot

The recent spurt of available treatments for prostate cancer may prove encouraging for patients and physicians, the price tags for these medications are giving insurers pause. Specifically, 47 percent of US payers indicate they plan to tightly manage combination therapies, according to a new survey of pharmacy and medical directors at national and regional plans.

In addition, 25 percent of national plans would require a patient to fail Johnson & Johnson?s (JNJ) Zytiga as monotherapy before approving a combination regimen, and 19 percent would cover both Zytiga and Xtandi ? the new treatment from Medivation (MDVN) and Astellas Pharma ? only if the drug was on their oncology clinical pathway. And roughly half of all plans will require prior authorization.

?Coverage won?t be automatic,? says Rhonda Greenapple, president of Reimbursement Intelligence, a market research firm that queried directors whose plans represent more than 100 million lives. ?Provenge brought a lot of attention to this area and payers are worried about cost of prostate care. They?re trying to standardize care and not have doctors use expensive therapies.?

The concerns reflect the higher-than-expected pricing for Xtandi, which was approved in September and carries a monthly price tag of $7,450, or $89,400 annually, based on wholesale costs. By comparison, Zytiga costs about $5,500 a month, or $66,000 a year, and the Provenge vaccine sold by Dendreon (DNDN) goes for $93,000.

An early indication into Xtandi uptake among physicians will emerge tomorrow when Medivation reports earnings, a moment that investors and many others have been waiting for eagerly, especially since Medivation and Astellas do not yet have data that can link their drug to either improved outcomes or cost savings.

Both Xtandi and Zytiga, which are pills, have similar overall survival benefit relative to placebo, and quality-of-life data. And both target men with prostate cancer that has spread elsewhere in the body or returned despite treatment designed to hamper testosterone production.

Source: http://www.pharmalot.com/2012/11/how-payers-view-combo-therapy-for-prostate-cancer/

vikings stadium breitbart dead db cooper fafsa branson missouri davy jones dead monkees

Friday, November 9, 2012

Timbuk2 Power Commute carries your gadgets, keeps 'em charged for $199 (hands-on)

Timbuk2 Power Commute carries your gadgets, keeps 'em charged for $199  handson

If you're like us, every one of your mobile devices could use a performance boost in one crucial area: battery life. Timbuk2 saw the exigency to keep phones, tablets, PMPs and cameras in the juice, and aims to meet that need with the Power Commute messenger bag announced earlier this year. And now you, dear reader can pick one up starting today for $199 from REI or through Timbuk2's website. Before you rush off to part with a pair of Benjamins for the bag and its waterproof Joey T1 portable power source, however, read on for our hands-on impressions.

Continue reading Timbuk2 Power Commute carries your gadgets, keeps 'em charged for $199 (hands-on)

Filed under:

Timbuk2 Power Commute carries your gadgets, keeps 'em charged for $199 (hands-on) originally appeared on Engadget on Thu, 08 Nov 2012 03:01:00 EDT. Please see our terms for use of feeds.

Permalink   |  sourceTimbuk2  | Email this | Comments


Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/WlhgYzdBV7I/

photos doomsday clock nate robinson sharia law sharia law new hampshire primary results molly sims

High School Love Stories

High School Love Stories

Will you find true love in high school? Or just a whole lot of drama? What will your High School Love Story be like?

Owner:

Game Masters:

This topic is an Out Of Character part of the roleplay, ?High School Love Stories?. Anything posted here will also show up there.

Topic Tags:

Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.


i dont usually join these kinds of roleplays, but may i reserve girl 1? i think i have a plan for her.

User avatar
MegaKooala12
Member for 0 years


also a question, does boy 4 know that girl 1 is in a relationship w/ boy 1?

User avatar
MegaKooala12
Member for 0 years


May I reserve girl 3 the girl seeing the teacher?

We all have a story to tell!

User avatar
cosmopolitanlove
Member for 0 years


Hm...screw it, I'll give it a go. I think I'll take an old character of mine from a similar RP and rework parts of him for this. I'll take one of the single males, please. I'll have a profile tomorrow at the latest.

EDIT: I'll wait till you have the rules and character sheet up before I start.

User avatar
Erik7622
Member for 1 years


Can I reserve a girl looking for love? THX. :)

If change is a part of life, why does it seem both cruel and gentle? -Tohru Honda (Fruits Basket)

User avatar
xLevesquex
Member for 0 years



Post a reply

RolePlayGateway is a site built by a couple roleplayers who wanted to give a little something back to the roleplay community. The site has no intention of earning any profit, and is paid for out of their own pockets.

If you appreciate what they do, feel free to donate your spare change to help feed them on the weekends. After selecting the amount you want to donate from the menu, you can continue by clicking on PayPal logo.

Who is online

Registered users: Abridged, Adantas*, Ahri*, Alasund De'astio, ali_rox96*, alight*, Angel's Whisper, Aniihya*, Animality Opera, Arcayne, Arch_Demon666, ArhaHitomi888*, Armageddon*, Ashes, barney_fife*, BBClock*, BrienaSkysong, BumbleDrop*, Caeruleus Lupis*, Calvazara*, Celaira*, Chloe De Luca, Chrome Shiny, Cienpher, Colors of Iris*, cosmopolitanlove, crilith, Crooked Thoughts, cucumbersome, cyanheadbands, delfiler, DestroytheOrcs, Digital_Muse*, dimon lord*, DuBois_Scarlett*, DustAndEchoes*, emotionless, EnigmaticallyEerie, Exabot [Bot], ExcellaStorm, FamishedPants*, FollowerOfDarkPaths*, Froggiepril, Frozen Soul, Geeky Panda*, Google [Bot], Google Adsense [Bot], Google Feedfetcher, Guilty Carrion*, Gypsy*, Heather1205, hellgirl**, HereMeNow, HitoriRaven*, Hyperiant*, Imbecile, Jakeperkins, Juular*, KrazyTigger, krumbla*, KulasLightShadow*, Kuroe, Layla*, Lloyd999*, Lornedo, Lux_Disraeli*, macheteshark, Magix, Marcus*, Marionette*, masato22*, Mela, Merchant*, Mishie, misstoniann*, mjlavalleejr*, Mr. Crow*, MSNbot Media, Nekohina*, nightwolf, NotAFlyingToy, OpalePhantasmagoria*, Patcharoo*, Porecomesis*, qbsuperstar03, RedWolfe*, Robinwing*, Rougeshadow*, RydeDawg*, Rylie Renae, Sage Akia, SakuraXx*, SarcasticIrony*, shadereen*, Shi-chan, Shiki29*, Shiva*, silverx, SkullJester*, Something?*, Sorella*, StormRider*, SuperNinjaRoo, Temperance*, Tenill, The Cynic*, The Painkiller, The Shadow*, The*Lucky*Teacup, Tiko*, TwiliXDragon, Tyce, Vanessa*, Vejisama*, Velgreth763, Vestiline, VitaminHeart*, WadeJackel*, Whispers..x*, wolfoftheage*, X64, XavierDantius32, Yahoo [Bot], YokoKitsune*, Yoru-Senpai, Zenia, zolzol*

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/U3_QnnzMTQ8/viewtopic.php

Karrueche Tran dodd frank Lark Voorhies Jennifer Livingston Orlando Cruz MLB Playoff Schedule arizona cardinals

LifeVantage First Quarter Fiscal 2013 Conference Call $LFVN

Thursday, November 08, 2012 @ 4:30 pm ET

Live Dial in number: 1-800-378-1475 or 1-719-325-2297

Replay Dial in number: 1-877-870-5176

A telephone replay of the conference call will be available through Nov 08, 2012

Passcode: 1384523

07
Nov

posted in: Twitter Detail Pages by selliott

Comments Off

Source: http://www.viavid.com/?p=2852

oscar predictions oscars nba all star game 2012 academy awards 2012 nominations academy awards independent spirit awards 2012 jan brewer

Thursday, November 8, 2012

Boeing not interested in partnering with Apple, after inking MOU with ...

ANA 787 10 150x150 Boeing not interested in partnering with Apple, after inking MOU with SamsungLast month Boeing announced it has signed a memorandum of understanding (MOU) with Samsung to explore??working together to research and develop technologies that improve in-flight entertainment and communications, as well as enhance factory productivity. Even though the two companies issued a press statement, details about the potentially ground-breaking arrangement were scarce, which is why the APEX editor?s blog reached out to Boeing for more information. I?m happy to report that the US airframer responded to our inquiry today. See below.

Question: Has Boeing ever stuck a ?joint technology research and development? agreement with other companies working in the inflight entertainment and communications space, including but not limited to Panasonic Avionics and Thales?

No, but while this MOU marks new opportunities for collaboration with Samsung Electronics, it builds on a history of partnership between Boeing and other Samsung entities, including Samsung Thales. Boeing works with the best suppliers in the industry to bring innovative in-flight entertainment solutions to our airline customers. But we?re always looking to develop new and exciting ways to bring the most value to our customers and the flying public.

Question: When does Boeing expect to finalize the MOU with Samsung, and begin exploring ways to improve inflight entertainment and connectivity?

The companies?are?working together to?put in place a master research collaboration agreement, and the scope of that agreement and the starting time are still to be determined.

Question: New Android-based in-seat IFE systems on offer from Panasonic and Thales (from 2013) are far lighter than legacy IFE systems. Additionally, a host of new entrants have entered the market with lightweight IFE solutions (AVOD, Portable and Wireless). In Boeing?s statement, Boeing says it will work with Samsung to ?initially start the development of advanced display and wireless networking technologies that offer more capabilities for passenger entertainment and ground-to-air communications, but are lighter and require less power?. Is Boeing not satisfied with the current IFE systems on offer? How much more weight ? and how much less power ? are you trying to achieve in your studies with Samsung?

We will not discuss proprietary business information, and it?s too early to say how we?ll work with Samsung Electronics in the future.

Question: What types of innovative technologies will be explored?

At this stage, both Boeing and Samsung Electronics are interested in pursuing technologies associated with next-generation wireless systems for on board applications. Samsung brings extensive knowledge of display, wireless network and low-power consumption technologies; Boeing brings knowledge of how wireless networks work in the airplane cabin environment, how they integrate with other systems on the airplane, and passenger behaviours and expectations. In addition, the companies will be exploring possible research and development projects associated with factory productivity enhancements. Samsung brings extensive knowledge of tablet PCs, wireless networks, electronic documents and mobile communications with smart phone technologies; Boeing brings knowledge of aerospace production processes and sensor integration in the production environment.

Question: Will you invite seat manufacturers to participate in the study? What about other players in the ?passenger experience? space?

It?s too early to speculate on specific projects or participants in projects. The announcement is about our excitement in agreeing to collaborate with Samsung to continuously improve our products and bring the most value to our customers.

Question: The statement also says Boeing hopes its studies with Samsung will ?enhance factory productivity?. What challenges are currently faced by Boeing, and how might productivity be improved?

Again, it?s too early to speculate on specific projects. We are very focused on finding ways to improve quality and drive greater efficiency in our factories.

Question: Is Boeing interested in striking a similar agreement with Samsung?s main competitor, Apple?

Not at this time.

Question: Boeing currently offers Panasonic and Thales embedded IFE as line-fit offerable on its aircraft. Does Boeing plan to make any other embedded systems offerable in the near-term? If so, who? Is Lumexis? fiber optics-based IFE in the running for line-fit offerability? What about IMS?s RAVE IFE system, which has scored a number of new customers, including Lufthansa.

Boeing continues to evaluate various systems based on our customer needs and the state of the systems? maturity. The offerability will be decided on a case-by-case basis.

Question: When would Boeing like to see the initial fruits of its labours with Samsung (i.e. What?s the timeline for the first product(s)?)

It is premature to discuss potential products and timeline for commercialization at this time.

Question: Qatar Airways, and more recently American Airlines, have talked about later-than-expected deliveries of the Boeing 787. Is it true that the time between cabin design freeze and eventual delivery (for these and other carriers) is so great ? and technology is moving so fast on the ground ? that a new paradigm is required whereby systems are not obsolete when they roll off the line?

This is an interesting question, but we?re not going to speculate about future developments.

Question: Would Boeing ever consider simply delivering green airplanes to the commercial market (as an option), and allowing carriers to make their own interiors/IFEC decisions through post-delivery mods? In other words, would Boeing be ever tempted to let #PaxEx changes/improvements be someone else?s proverbial headache?

This is an interesting question, but we?re not going to speculate about future developments.

Source: http://blog.apex.aero/cabin-interior/boeing-interested-partnering-apple-inking-mou-samsung/

jon huntsman bit coin huntsman w.e. episodes idris elba kelsey grammer

The Different Aspects Of A Personal Injury Claim

Personal InjuryWhenever an individual wants to be compensated for the injuries they incurred because of a company?s or individual?s negligent behavior, they will file a personal injury claim and usually hire an attorney that specializes in these types of legal issues. These claims oftentimes include emotional/psychological damage such as anxiety and distress. They may also contain physical damage such long or short-term disabilities, pain and suffering, and wrongful death. These types of claims were developed so that the victim of negligent behavior could be compensated for their injury, lost time on the job, and any healthcare bills that resulted from their injuries.

Being Represented in Court

It is always a wise decision to seek legal representation anytime this type of situation arises. Hiring an attorney who is experienced in the applicable laws and can skillfully defend the injured victim against the big insurance companies is a better choice than just hiring any basic lawyer. Depending on the nature of the case, personal injury attorneys will work on a contingency basis or receive a percentage of the financial settlement that results from the person being awarded for the injuries and damages that occurred.

Formula for Damages

When claims of this nature are being filed against the insurance company that is involved in the case, an adjuster from that firm will offer some type of settlement to the injured victim. It is at this point in time that the negotiations towards a final amount of compensation usually begin. The adjuster will usually calculate the amount of compensation to be offered based on what is called a damages formula.

The medical bills related to the injury serves as the formula base figure and the adjuster will then add whatever income the victim has lost as a result of the injury. The insurance adjuster must also add in a monetary amount for pain and suffering and other related ?general? damages. On the average, the total dollar amount to this point will be multiplied by 1? or 2 times if the injuries are minor. However, that multiplier will be increased when the case involves major or serious injuries and wrongful death.

Finding the right personal injury attorney will give you a better chance of winning your case against an insurance company so that you receive fair compensation for damages. The attorneys at GetMeJustice.com have over 100 years of combined experience with this types of cases and can help you with your situation. Please visit our website for more information.

Source: http://www.getmejustice.com/injury-law-firm-blog/post/762/The-Different-Aspects-Of-A-Personal-Injury-Claim

droid 4 tom brady sister dad shoots daughters laptop brandon jennings channing tatum the vow review luol deng

NJ man swept away by Sandy left behind note

(AP) ? Nearly naked and soaking wet, a New Jersey man who took refuge in a stranger's house after he was swept away by Superstorm Sandy left behind a note to his father in case he didn't survive.

The man, identified only as Mike, swam for his life as waves and currents gripped him in Barnegat Bay after he walked outside when the storm destroyed part of his home in the Green Island section of Toms River.

"I was in the middle of nowhere and there were no lights and the first house I went into was flooded and I just really needed, really needed a break because the waves were going over my head," he told radio station WOBM in Toms River.

He eventually ended up at a stranger's home, tired, thirsty and suffering from hypothermia. He wrapped himself in towels and wrote a letter to the homeowner saying he didn't take anything. He also left a phone number to tell his father that he loved him because he was certain he was going to die.

The letter read: "Who ever reads this I'm DIEING - I'm 28 yrs old my name is Mike. I had to break in to your house. I took blankets off the couch. I have hypothermia. I didn't take any thing. A wave thru me out of my house down the block. I don't think I'm going to make it. The water outside is 10ft deep at least. There's no resue. Tell my dad I love him and I tryed geting out. His ... name is Tony. I hope u can read this I'm in the dark. I took a black jacket too. Goodbye. God all mighty help me."

The homeowner returned to find the note but not the man, and she posted a photo of the note on her Facebook page. The radio station tracked Mike down.

He said he was rescued by a man named Frank on a personal watercraft who drove him to a house, gave him clothes and hot chocolate.

Mike was reunited with his family in Bergen County

___

Information from: WOBM-AM, http://www.wobmam.com

___

Information from: WOBM-AM, http://www.wobmam.com

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-11-06-Superstorm%20Sandy-Letter/id-58f9d60e13b0454b9acb6b4878060ca9

London 2012 Synchronized Swimming London 2012 hurdles Taylor Kinney Beach Volleyball Olympics 2012 Jessica Ennis Oscar Pistorius Aliya Mustafina